Article

Regulatory T cell stability determines the efficiency of bile duct regeneration during cholangitis

2025-04-08

Abstract excerpt

<h4>Background and Aims</h4> Cholangiopathies such as Primary Sclerosing Cholangitis (PSC) cause damage to the bile ducts and fibrosis with no effective cure. A reduction and impairment in the function of regulatory T cells (Tregs) occurs in PSC. Yet, it is currently unknown what consequence this has on bile duct regeneration. We investigate whether Tregs regulate bile duct regeneration and the dynamics of Tregs...

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Literature Corpus work: 8a23259a-2738-538e-a0e0-e829a2c01ce6
DOI: 10.1101/2025.04.02.646748

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