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Article

Biliary fibrosis drives liver repopulation and phenotype transition of transplanted hepatocytes.

Journal of hepatology - 1 Jun 2016

Yovchev Mladen I, Locker Joseph, Oertel Michael

Abstract excerpt

BACKGROUND & AIMS: Current research focuses on developing alternative strategies to restore decreased liver mass prior to the onset of end-stage liver disease. Cell engraftment/repopulation requires regeneration in normal liver, but we have shown that severe liver injury stimulates repopulation without partial hepatectomy (PH). We have now investigated whether a less severe injury, secondary biliary fibrosis,...

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Identifiers

PMID: 26855174
DOI: 10.1016/j.jhep.2016.01.036
PMCID: PMC5137249

Genes

SPP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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