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An immunobiliary single-cell atlas resolves crosstalk of type 2 cDCs and γδT cells in cholangitis

2025-07-15

Abstract excerpt

<h4>Background and aims</h4> The immunobiliary niche serves as a reservoir of tissue-resident immune cells, yet the role of unconventional T cells during cholangitis remains poorly understood. Here, we connect cell state dynamics of type 2 conventional dendritic cells (cDC2) in cholangitis with site-specific γδ T17 responses in liver and draining lymph nodes (LN). <h4>Methods</h4> The 0.1% Diethoxycarbonyl-1,4...

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Literature Corpus work
a3228e3f-c98c-5db9-82a7-1bd712e29ae9
DOI
10.1101/2025.07.10.664083
Open publication

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An immunobiliary single-cell atlas resolves crosstalk of type 2 cDCs and γδT cells in cholangitisDOI 10.1101/2025.07.10.664083
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