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Article

Successful treatment of murine autoimmune cholangitis by parabiosis: Implications for hematopoietic therapy.

Journal of autoimmunity - 1 Jan 2016

Yang Jing-Bo, Wang Yin-Hu, Yang Wei, Lu Fang-Ting, Ma Hong-Di, Zhao Zhi-Bin, Jia Yan-Jie, Tang Wei, Tsuneyama Koichi, Ridgway William M, Gershwin M Eric, Lian Zhe-Xiong

Abstract excerpt

There is a significant unmet need in the treatment of primary biliary cirrhosis (PBC) despite significant data on the effector pathways that lead to biliary duct damage. We focused attention on a murine model of PBC, the dominant negative transforming growth factor β receptor II (Tg) mice. To further define the pathways that lead to biliary pathology in these mice, we developed Tg mice deleted of CD4 cells...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26432598
DOI: 10.1016/j.jaut.2015.09.002
PMCID: PMC4829433

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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