Article
Depletion of Foxp3+ Regulatory T Cells Promotes Profibrogenic Milieu of Cholestasis-Induced Liver Injury.
Digestive diseases and sciences - 1 Jul 2015
Roh Yoon Seok, Park Surim, Lim Chae Woong, Kim Bumseok
Abstract excerpt
BACKGROUND: Accumulating evidence suggests that Foxp3+ regulatory T (Treg) cells act as inhibitory mediators of inflammation; however, the in vivo mechanism underlying this protection remains elusive in liver diseases. AIMS: To clarify the in vivo role of Foxp3+ Treg cells in liver fibrosis, we u...
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