Article

PRO-FitS: a novel phenotypic assay to identify enhancers of proteostasis in <i>C. elegans</i>

2026-01-24

Abstract excerpt

The prevalence of neurodegenerative diseases (NDs) continues to rise with the aging of populations worldwide, representing a pressing need for the establishment of therapeutic strategies. Maintaining proteostasis is crucial for healthy aging, as the accumulation of misfolded and aggregated proteins is a key contributor to age-related cellular dysfunction and disease. This study introduces a novel phenotypic assay...

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Literature Corpus work: 89fff82c-c112-588d-b8dd-32b3587d9ed1
DOI: 10.64898/2026.01.22.701023

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