Article
C. elegans screening strategies to identify pro-longevity interventions.
Mechanisms of ageing and development - 1 Jul 2016
Maglioni Silvia, Arsalan Nayna, Ventura Natascia
Abstract excerpt
Drugs screenings in search of enhancers or suppressors of selected readout(s) are nowadays mainly carried out in single cells systems. These approaches are however limited when searching for compounds with effects at the organismal level. To overcome this drawback the use of different model organisms to carry out modifier screenings has exponentially grown in the past decade. Unique characteristics such as easy...
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