Abalone peptide increases stress resilience and cost‐free longevity via SKN ‐1‐governed transcriptional metabolic reprogramming in C. elegans

Abstract excerpt

A major goal of healthy aging is to prevent declining resilience and increasing frailty, which are associated with many chronic diseases and deterioration of stress response. Here, we propose a loss-or-gain survival model, represented by the ratio of cumulative stress span to life span, to quantify stress resilience at organismal level. As a proof of concept, this is demonstrated by reduced survival resilience in...

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