Article

BCAT1 regulates glioblastoma cell plasticity and contributes to immunosuppression

2023-04-29

Abstract excerpt

Glioblastoma is the most common malignant brain tumor in adults. Cellular plasticity and the poorly differentiated features result in a fast relapse of the tumors following treatment. Moreover, the immunosuppressive microenvironment proved to be a major obstacle to immunotherapeutic approaches. Branched-chain amino acid transaminase 1 (BCAT1) is a metabolic enzyme that converts branched-chain amino acids into bran...

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Literature Corpus work: 8998b5e7-c5e7-5767-a20d-ce209ee81aaf
DOI: 10.1101/2023.04.28.538788

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