Article
Novel roles of VAT1 expression in the immunosuppressive action of diffuse gliomas.
Cancer immunology, immunotherapy : CII - 1 Sept 2021
Yang Pei, Wang Kuanyu, Zhang Chuanbao, Wang Zhiliang, Liu Qi, Wang Jiangfei, Jiang Tao, Shan Xia
Abstract excerpt
Standard treatment regimen of gliomas has almost reached a bottleneck in terms of survival benefit. Immunotherapy has been explored and applied in glioma treatment. Immunosuppression, as a hallmark of glioma, could be alleviated by inhibiting certain abnormally expressed biomarkers. Here, transcriptome data of 325 whole grade gliomas were collected from the CGGA database. The TCGA RNA sequencing database was used...
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