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Article

Novel prognostic biomarker TBC1D1 is associated with immunotherapy resistance in gliomas

11 Mar 2024

Abstract excerpt

Background: Glioma, an aggressive brain tumor, poses a challenge in understanding the mechanisms of treatment resistance, despite promising results from immunotherapy. Methods: We identified genes associated with immunotherapy resistance through an analysis of The Cancer Genome Atlas (TCGA), Chinese Glioma Genome Atlas (CGGA), and Gene Expression Omnibus (GEO) databases. Subsequently, qRT-PCR and western blot...

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PMID: 38529286
DOI: 10.3389/fimmu.2024.1372113

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