Article

Minimally invasive monitoring of clonal evolution through integrated single cell and ctDNA analysis

2026-07-30

Abstract excerpt

Circulating cell-free DNA (cfDNA) offers a minimally invasive lens into tumor evolution. However, the accurate quantification of clonal composition from cfDNA remains challenging. Existing methods for clone tracking using liquid biopsies are constrained by issues such as their reliance on bulk tissue references, incomplete representations of clonal architecture or limited breadth of mutation panels. To address the...

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Literature Corpus work: 89482cde-4040-5cd1-a567-38a2bf475baa
DOI: 10.64898/2026.07.29.741620

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