Article

A Transferable Model For Chromosome Architecture

2016-04-13

Abstract excerpt

In vivo , the human genome folds into a characteristic ensemble of three-dimensional structures. The mechanism driving the folding process remains unknown. We report a theoretical model for chromatin ( Mi nimal Chro matin M odel) that explains the folding of interphase chromosomes and generates chromosome conformations consistent with experimental data. The energy landscape of the model was derived by using the...

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Identifiers and source

Literature Corpus work: 893a828d-9fa8-55d0-b193-6be36fe2aee3
DOI: 10.1101/048439

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