Article
A maximum-entropy model for predicting chromatin contacts.
PLoS computational biology - 1 Feb 2018
Farré Pau, Emberly Eldon
Abstract excerpt
The packaging of DNA inside a nucleus shows complex structure stabilized by a host of DNA-bound factors. Both the distribution of these factors and the contacts between different genomic locations of the DNA can now be measured on a genome-wide scale. This has advanced the development of models aimed at predicting the conformation of DNA given only the locations of bound factors-the chromatin folding problem....
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