Article

SOX10 and microRNAs: decoding their interplay in regulating melanoma plasticity

2024-10-14

Abstract excerpt

Recent studies show that the dysregulation of the transcription factor SOX10 is essential for development and progression of melanoma. MicroRNAs (miRNAs) can regulate the expression of transcription factors at the post-transcriptional level. The interactions between SOX10 and its targeting miRNAs form network motifs such as feedforward and feedback loops. Such motifs can result in non-linear dynamics in gene expre...

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Literature Corpus work: 88c5c70f-c155-5b5a-8f75-b468d62e296b
DOI: 10.1101/2024.10.09.617381

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