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Article

SOX9 is a dose-dependent metastatic fate determinant in melanoma

14 Jan 2019

Abstract excerpt

BACKGROUND: In this research, we aimed to resolve contradictory results whether SOX9 plays a positive or negative role in melanoma progression and determine whether SOX9 and its closely related member SOX10 share the same or distinct targets in mediating their functions in melanoma. METHODS: Immunofluorescence, TCGA database and qPCR were used to analyze the correlation between the expression patterns and levels...

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PMID: 30642390
DOI: 10.1186/s13046-018-0998-6

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