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The N-terminus of <i>Plasmodium falciparum</i> Circumsporozoite Protein Contains Three Non-Overlapping Murine B-cell Epitope Regions

2024-01-20

Abstract excerpt

The generation of an anti-malarial vaccine that produces broad, potent, and durable responses is highly desirable to control the burden of Plasmodium falciparum disease. Current vaccines have offered modest efficacy ranging from 50%-70%, likely associated with antibody responses that are relatively short lived and strain specific. Currently approved malaria vaccines, RTS,S and R21, target the repeat region and C-...

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Literature Corpus work
884bc1ad-740e-5044-aaca-8880c9f11769
DOI
10.1101/2024.01.18.574923
Open publication

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The N-terminus of <i>Plasmodium falciparum</i> Circumsporozoite Protein Contains Three Non-Overlapping Murine B-cell Epitope RegionsDOI 10.1101/2024.01.18.574923
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