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Molecular and functional properties of human <i>Plasmodium falciparum</i> CSP C-terminus antibodies

2023-01-19

Abstract excerpt

<h4>ABSTRACT</h4> Human monoclonal antibodies (mAbs) against the central repeat and junction domain of Plasmodium falciparum circumsporozoite protein (PfCSP) have been studied extensively to guide malaria vaccine design compared to antibodies against the PfCSP C terminus. Here, we describe the molecular characteristics and protective potential of a panel of 73 germline and mutated human mAbs against the highly i...

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Identifiers and source

Literature Corpus work
08989248-d74e-5596-a92c-2ef7d59b43a1
DOI
10.1101/2023.01.19.524692
Open publication

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Molecular and functional properties of human <i>Plasmodium falciparum</i> CSP C-terminus antibodiesDOI 10.1101/2023.01.19.524692
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