Article

Equalizing epigenetically imprinted centromeres in early mammalian embryos

2022-10-28

Abstract excerpt

<h4>Summary</h4> The CENP-A histone variant epigenetically defines centromeres, where its levels and locations are precisely maintained through mitotic cell divisions. However, differences in centromere CENP-A propagation in soma versus female/male germline remains poorly understood. Here, we generated C enpa mScarlet mice and followed CENP-A dynamics in gametes, zygotes, and embryos. We found that, unlike somat...

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Literature Corpus work: 8ef8c11a-a943-5e3c-9644-4431ac214432
DOI: 10.1101/2022.10.27.514094

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