Article

Systematic characterization of chromodomain proteins reveals an H3K9me1/2 reader regulating aging in <i>C. elegans</i>

2022-08-12

Abstract excerpt

<h4>ABSTRACT</h4> The chromatin organization modifier domain (chromodomain) is an evolutionally conserved motif across eukaryotic species. The chromodomain mainly functions as a histone methyl-lysine reader to modulate gene expression, chromatin spatial conformation and genome stability. Mutations or aberrant expression of chromodomain proteins can result in cancer and other human diseases. Here, we systematicall...

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Literature Corpus work: b9241966-0587-52e8-9c18-ebe853d487ef
DOI: 10.1101/2022.08.10.503448

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