Article

Locus-specific H3K9me3 gain in aged somatic tissues in Caenorhabditis elegans

2021-02-22

Abstract excerpt

Epigenetic alterations occur as organisms age, and lead to chromatin deterioration, loss of transcriptional silencing and genomic instability. Dysregulated epigenome has been linked to increased susceptibility to age-related disorders. We aim to characterize the age-dependent changes of the epigenome and, in turn, to understand epigenetic processes that drive aging phenotypes. In this study, we focused on the agin...

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Literature Corpus work: 7789c416-8b01-5d51-a8dd-a088e62f5112
DOI: 10.1101/2021.02.22.432236

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