Article

Host-secreted lactate during respiratory viral infection diminishes macrophage antibacterial activity through metabolic reprogramming

2026-07-16

Abstract excerpt

In polymicrobial infections, how the host recognizes and responds to pathogens influences which species will persist to cause chronic infections. The human respiratory tract is a common anatomical site for viral-bacterial co-infections, where primary viral infections predispose to secondary bacterial infections, leading to increased morbidity and mortality. Additionally, co-infections are disproportionately preval...

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Literature Corpus work: 871f8247-1752-5bbd-9ac9-f059bf4503df
DOI: 10.64898/2026.07.11.737940

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