Article

Predicting Mean Ribosome Load for 5’UTR of any length using Deep Learning

2020-06-16

Abstract excerpt

The 5’ untranslated region plays a key role in regulating mRNA translation and consequently protein abundance. Therefore, accurate modeling of 5’UTR regulatory sequences shall provide insights into translational control mechanisms and help interpret genetic variants. Recently, a model was trained on a massively parallel reporter assay to predict mean ribosome load (MRL) - a proxy for translation rate - directly fr...

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Literature Corpus work: 86de4417-9e82-5a9d-b9b1-f1694f3d4aca
DOI: 10.1101/2020.06.15.152728

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