Article

Towards improving full-length ribosome density prediction by bridging sequence and graph-based representations

2024-04-11

Abstract excerpt

Translation elongation plays an important role in regulating protein concentrations in the cell, and dysregulation of this process has been linked to several human diseases. In this study, we use data from ribo-seq experiments to model ribosome densities, and in turn, predict the speed of translation. The proposed method, RiboGL, combines graph and recurrent neural networks to account for both graph and sequence-b...

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Literature Corpus work: d22deb33-b4ba-5884-a2fb-bf68174193a3
DOI: 10.1101/2024.04.08.588507

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