Article

Predicting the translation efficiency of messenger RNA in mammalian cells

2024-08-11

Abstract excerpt

The degree to which translational control is specified by mRNA sequence is poorly understood in mammalian cells. Here, we constructed and leveraged a compendium of 3,819 ribosomal profiling datasets, distilling them into a transcriptome-wide atlas of translation efficiency (TE) measurements encompassing >140 human and mouse cell types. We subsequently developed RiboNN, a multitask deep convolutional neural network...

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Literature Corpus work: 362c9034-4af6-5249-96f8-9031f22701a3
DOI: 10.1101/2024.08.11.607362

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