Article

A Theory for High-Throughput Genetic Interaction Screening

2022-10-05

Abstract excerpt

Systematic, genome-scale genetic screens have been instrumental for elucidating genotype-phenotype relationships, but approaches for probing genetic interactions have been limited to at most ∼100 pre-selected gene combinations in mammalian cells. Here, we introduce a theory for high-throughput genetic interaction screens. The theory extends our recently developed Multiplexing using Spectral Imaging and Combinatori...

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Literature Corpus work: 86b333fc-8f1e-5b8d-ac8e-ab4f01bee6b9
DOI: 10.1101/2022.10.05.510977

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