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Highly replicated experiments studying complex genotypes using nested DNA barcodes.

G3 (Bethesda, Md.) - 3 Sept 2025

Monge Molly, Giovanetti Simone M, Ravishankar Apoorva, Sadhu Meru J

Abstract excerpt

Many biological experiments involve studying the differences caused by genetic modifications, including genotypes composed of modifications at more than 1 locus. However, as the genotypes increase in number and complexity, it becomes a major challenge to independently generate and track the necessary number of biological replicate samples. A major development in genetic studies of large numbers of genotypes has...

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PMID: 40657759
DOI: 10.1093/g3journal/jkaf146
PMCID: PMC12405881

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