Article

Immune landscapes predict chemotherapy resistance and immunotherapy response in acute myeloid leukemia

2019-07-26

Abstract excerpt

This study dissected the complexity of the immune architecture of acute myeloid leukemia (AML) at high resolution and assessed its influence on therapeutic response. Using 387 primary bone marrow samples from three discovery cohorts of children and adults with AML, we defined immune-infiltrated and immune-depleted disease subtypes and unraveled critical differences in immune gene expression across age groups and d...

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Literature Corpus work: 0687c40c-aa30-5a07-8a6f-fc8747a43a2f
DOI: 10.1101/702001

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