Article

Mining single-cell transcriptomic data reveals distinct T-cell population in pediatric B-ALL and AML at diagnosis

2026-01-10

Abstract excerpt

<h4>ABSTRACT</h4> Immunotherapy represents a promising strategy to improve outcomes in pediatric leukemia; however, its efficacy remains considerably lower in acute myeloid leukemia (AML) compared with B-cell acute lymphoblastic leukemia (B-ALL). To characterize T-cell subsets in AML and B-ALL at diagnosis, we took advantage of existing data sets and performed an integrated single-cell RNA sequencing (scRNA-seq)...

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Literature Corpus work: 99158947-340d-5d20-8c1c-08d2ad7c167c
DOI: 10.64898/2026.01.09.698676

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