Article

Pediatric acute myeloid leukemia tumor composition predicts patient outcomes at diagnosis and reveals mechanisms of resistance to chemotherapy

2026-01-23

Abstract excerpt

<title>Abstract</title> <p>Although most pediatric acute myeloid leukemia (pAML) patients achieve complete remission with standard-of-care chemotherapy, overall outcomes are poor, and 40% will eventually relapse. Improved methods for risk assessment at diagnosis and alternative therapies are needed to improve outcomes for these patients. Toward these objectives, we characterized the clonal composition of pAMLs, i...

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Literature Corpus work: 17f4c075-91b4-5ca7-ac91-47f10f23e7b9
DOI: 10.21203/rs.3.rs-4669225/v1

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