Article

Signatures of chromosomal instability in human cancers

2020-01-01

Abstract excerpt

Chromosomal instability (CIN), defined as the process of losing or gaining whole or parts of chromosomes, is one of the earliest molecular characteristics to be described in cancer. Since its detection by light microscopy in the late 19th century, technological advances have facilitated the observation of CIN at increasing resolution, revealing an extreme genomic complexity which we are only beginning to understan...

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Literature Corpus work: c40883b2-c3b7-5ffb-be5a-8956865f7463
DOI: 10.17863/cam.69594

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