Article

A survey of CIN measures across mechanistic models

2023-06-15

Abstract excerpt

Chromosomal instability (CIN) is the persistent reshuffling of cancer karyotypes via chromosome mis-segregation during cell division. In cancer, CIN exists at varying levels that have differential effects on tumor progression. However, mis-segregation rates remain challenging to assess in human cancer despite an array of available measures. We evaluated measures of CIN by comparing quantitative methods using speci...

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Literature Corpus work: d5840cb6-a7ed-549a-8a60-a279a552aaef
DOI: 10.1101/2023.06.15.544840

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