Article

Statistical inference reveals the role of length, breathing, and nucleotide identity in V(D)J nucleotide trimming

2022-12-12

Abstract excerpt

To appropriately defend against a wide array of pathogens, humans somatically generate highly diverse repertoires of B cell and T cell receptors (BCRs and TCRs) through a random process called V(D)J recombination. Receptor diversity is achieved during this process through both the combinatorial assembly of V(D)J-genes and the junctional deletion and insertion of nucleotides. While the Artemis protein is often rega...

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Literature Corpus work: 85a7a11a-97b5-51ad-9a2d-49fda62a41cb
DOI: 10.1101/2022.12.08.519635

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