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Article

Identifying highly mutated IGHD genes in the junctions of rearranged human immunoglobulin heavy chain genes.

Journal of immunological methods - 31 Jul 2007

Jackson Katherine J L, Gaëta Bruno A, Collins Andrew M

Abstract excerpt

The reliable identification of IGHD genes within human immunoglobulin heavy chains is challenging with up to one third of rearrangements having no identifiable IGHD gene. The short, mutated IGHD genes are generally assumed to be indistinguishable from the N-REGIONS of non-template encoded nucleotides that surround them. In this study we have characterised N-REGIONS, demonstrating the importance of nucleotide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17553518
DOI: 10.1016/j.jim.2007.04.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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