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Article

Identification and Manipulation of the Molecular Determinants Influencing Poliovirus Recombination

7 Feb 2013

Abstract excerpt

The control and prevention of communicable disease is directly impacted by the genetic mutability of the underlying etiological agents. In the case of RNA viruses, genetic recombination may impact public health by facilitating the generation of new viral strains with altered phenotypes and by compromising the genetic stability of live attenuated vaccines. The landscape of homologous recombination within a given...

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PMID: 23408891
DOI: 10.1371/journal.ppat.1003164

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