Article

Comprehensive analysis of mutational signatures in pediatric cancers

2021-09-29

Abstract excerpt

Analysis of mutational signatures can reveal the underlying molecular mechanisms of the processes that have imprinted the somatic mutations found in a cancer genome. Here, we present a pan-cancer mutational signatures analysis of single base substitutions (SBS) and small insertion and deletions (ID) in pediatric cancers encompassing 537 whole genome sequenced tumors from 20 molecularly defined cancer subtypes. We...

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Identifiers and source

Literature Corpus work: 85303259-aa6b-59fb-bf0b-a3fa9701af9b
DOI: 10.1101/2021.09.28.462210

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