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Genomic alterations in pediatric tumors: clinical relevance and translational insights

13 Aug 2026

Abstract excerpt

BACKGROUND: Cancer is the leading cause of disease-related mortality in children. Next-generation sequencing (NGS) has emerged as a critical tool in precision oncology, enabling the identification of somatic genomic alterations that may inform diagnosis, prognosis, and therapy. This study evaluated the clinical utility of NGS in Israeli pediatric cancer patients. METHODS: We conducted a retrospective analysis of...

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PMID: 42595821
DOI: 10.1038/s41390-026-05338-0

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