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Article

Somatic structural variation signatures in pediatric brain tumors.

Cell reports - 31 Oct 2023

Yang Yang, Yang Lixing

Abstract excerpt

Brain cancer is the leading cause of cancer-related death in children. Somatic structural variations (SVs), large-scale alterations in DNA, remain poorly understood in pediatric brain tumors. Here, we detect a total of 13,199 high-confidence somatic SVs in 744 whole-genome sequences of pediatric brain tumors from the Pediatric Brain Tumor Atlas. The somatic SV occurrences have tremendous diversity among the...

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Identifiers

PMID: 37851574
DOI: 10.1016/j.celrep.2023.113276
PMCID: PMC10748741

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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