Article

Somatic structural variation signatures in pediatric brain tumors

2023-05-26

Abstract excerpt

<h4>Summary</h4> Brain cancer is the leading cause of cancer-related death in children. Somatic structural variations (SVs), large scale alterations in DNA, remain poorly understood in pediatric brain tumors. Here, we detect a total of 13,199 high confidence somatic SVs in 744 whole-genome-sequenced pediatric brain tumors from Pediatric Brain Tumor Atlas. The somatic SV occurrences have tremendous diversity among...

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Literature Corpus work: 0d126405-56e7-5bde-8a22-879c1d2afce4
DOI: 10.1101/2023.05.18.23290139

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