Article

Interleukin-17 directly triggers Epstein-Barr virus lytic reactivation in latently infected human B cells

2025-12-19

Abstract excerpt

<h4>ABSTRACT</h4> Epstein-Barr virus (EBV) is a ubiquitous human gammaherpesvirus implicated in a wide spectrum of inflammatory and malignant diseases. Although EBV toggles between latent and lytic states, the host cues that control this switch remain incompletely defined. Interleukin-17A (IL-17A; hereafter IL-17), a signature Th17 cytokine, is abundant in EBV-associated tissues, and EBV products can augment IL-1...

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Literature Corpus work: 85053575-32a0-5f02-9976-5e7da302f814
DOI: 10.64898/2025.12.19.695390

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