Article

Epstein-Barr virus inactivates the transcriptome and disrupts the chromatin architecture of its host cell in the first phase of lytic reactivation

2019-03-20

Abstract excerpt

<h4>ABSTRACT</h4> Epstein-Barr virus (EBV), a herpes virus also termed HHV 4 and the first identified human tumor virus, establishes a stable long-term latent infection in human B cells, its preferred host. Upon induction of EBV’s lytic phase the latently infected cells turn into a virus factory, a process, that is governed by EBV. In the lytic, productive phase all herpesviruses ensure the efficient induction of...

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Literature Corpus work: f3d70528-a800-51a9-992a-9f77f3a5afa8
DOI: 10.1101/573659

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