Article

Germinal Center Cytokines Driven Epigenetic Control of Epstein-Barr Virus Latency Gene Expression

2024-01-03

Abstract excerpt

Epstein-Barr virus (EBV) persistently infects 95% of adults worldwide and is associated with multiple human lymphomas that express characteristic EBV latency programs used by the virus to navigate the B-cell compartment. Upon primary infection, the EBV latency III program, comprised of six Epstein-Barr Nuclear Antigens (EBNA) and two Latent Membrane Protein (LMP) antigens, drives infected B-cells into germinal cen...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b84a2bc4-f1e1-5afb-a850-0dae697c2b10
DOI: 10.1101/2024.01.02.573986

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Germinal Center Cytokines Driven Epigenetic Control of Epstein-Barr Virus Latency Gene ExpressionDOI 10.1101/2024.01.02.573986Read

Germinal center cytokine driven epigenetic control of Epstein-Barr virus latency gene expressionSemantic proximity Read

EBV Latency Programs: Molecular and Epigenetic Regulation and Its Role in Disease PathogenesisSemantic proximity Read

RNA Sequencing Analyses of Gene Expression during Epstein-Barr Virus Infection of Primary B LymphocytesSemantic proximity Read

Multiple viral microRNAs regulate interferon release and signaling early during infection with Epstein-Barr virusSemantic proximity Read

Epigenetic lifestyle of Epstein-Barr virusSemantic proximity Read

Epstein-Barr virus reprograms human B-lymphocytes immediately in the pre-latent phase of infectionSemantic proximity Read

Epstein–Barr virus reprograms human B lymphocytes immediately in the prelatent phase of infectionSemantic proximity Read

Histone loaders CAF1 and HIRA restrict Epstein-Barr virus B-cell lytic reactivationSemantic proximity Read

Regulation and dysregulation of Epstein–Barr virus latency: Implications for the development of autoimmune diseasesSemantic proximity Read

Epigenetic Mechanisms in Latent Epstein-Barr Virus Infection and Associated CancersSemantic proximity Read

Characterization of Target Gene Regulation by the Two Epstein-Barr Virus Oncogene LMP1 Domains Essential for B-cell TransformationSemantic proximity Read

Epstein–Barr virus nuclear antigen 3A partially coincides with EBNA3C genome-wide and is tethered to DNA through BATF complexesSemantic proximity Read