Molecular Basis of Epstein–Barr Virus Latency Establishment and Lytic Reactivation

doi:10.3390/v13122344

Article

Molecular Basis of Epstein–Barr Virus Latency Establishment and Lytic Reactivation

23 Nov 2021

Abstract excerpt

Epstein-Barr virus (EBV) is a causative agent of infectious mononucleosis and several types of cancer. Like other herpesviruses, it establishes an asymptomatic, life-long latent infection, with occasional reactivation and shedding of progeny viruses. During latency, EBV expresses a small number of viral genes, and exists as an episome in the host-cell nucleus. Expression patterns of latency genes are dependent on...

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.