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Article

Regulation of IL-17 in autoimmune diseases by transcriptional factors and microRNAs

14 Jul 2015

Abstract excerpt

In recent years, IL-17A (IL-17), a pro-inflammatory cytokine, has received intense attention of researchers and clinicians alike with documented effects in inflammation and autoimmune diseases. IL-17 mobilizes, recruits and activates different cells to increase inflammation. Although protective in infections, overproduction of IL-17 promotes inflammation in autoimmune diseases such as multiple sclerosis,...

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PMID: 26236331
DOI: 10.3389/fgene.2015.00236

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