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Article

Gammaherpesvirus Usurps Host IL-17 Signaling To Support the Establishment of Chronic Infection

5 Apr 2021

Abstract excerpt

Gammaherpesviruses establish lifelong infections in a majority of humans and are associated with B cell lymphomas. IL-17A is a host cytokine that plays a well-established role in the clearance of bacterial and fungal infections; however, the role of IL-17A in viral infections is poorly understood. In this study, we show that IL-17A signaling promoted the establishment of chronic gammaherpesvirus infection...

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PMID: 33824206
DOI: 10.1128/mbio.00566-21

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