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Article

Germinal center cytokine driven epigenetic control of Epstein-Barr virus latency gene expression

29 Apr 2024

Abstract excerpt

Epstein-Barr virus (EBV) persistently infects 95% of adults worldwide and is associated with multiple human lymphomas that express characteristic EBV latency programs used by the virus to navigate the B-cell compartment. Upon primary infection, the EBV latency III program, comprised of six Epstein-Barr Nuclear Antigens (EBNA) and two Latent Membrane Protein (LMP) antigens, drives infected B-cells into germinal...

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PMID: 38683861
DOI: 10.1371/journal.ppat.1011939

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