Article

Loss of REST in Breast Cancer Promotes Tumor Progression Through Estrogen Sensitization, MMP24 and CEMIP Overexpression.

2021-03-31

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Breast cancer is the most common malignancy in women, and is both pathologically and genetically heterogeneous, making early detection and treatment difficult. A subset of breast cancers express normal levels of <italic>REST</italic> (repressor element 1 silencing transcription factor) mRNA but lack functional REST protein. Loss of REST function is seen in ~20%...

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Literature Corpus work: 849ff2e4-523e-5929-8935-add5a51faa11
DOI: 10.21203/rs.3.rs-345857/v1

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