Article

Loss of the repressor REST affects progesterone receptor function and promotes uterine leiomyoma pathogenesis

2022-04-11

Abstract excerpt

Uterine Leiomyomas (UL) are benign tumors that arise in the myometrial layer of the uterus. The standard treatment option for UL is hysterectomy, although hormonal therapies such as selective progesterone receptor modulators are often used as temporary treatment options to reduce symptoms or slow the growth of tumors. However, since the pathogenesis of UL is poorly understood and most hormonal therapies are not ba...

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Literature Corpus work: 1ff38e4c-1b9f-5f49-8335-a763a9b4b0b2
DOI: 10.1101/2022.04.11.487902

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