Article

Sleep Phenotypes of α-Synucleinopathies and Tauopathies with Parkinsonism

2025-03-14

Abstract excerpt

<h4>Introduction</h4> In neurodegenerative Parkinsonism, biomarkers of α-synucleinopathy (Syn) or tauopathy (Tau) are an unmet need. Rapid eye movement (REM) sleep behavior disorder (RBD) strongly indicates Syn. However, it remains unknown if sleep features other than RBD could reflect underlying neuropathology. Here we assess sleep phenotypes of Syn or Tau in neurodegenerative Parkinsonism and explore their prope...

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Literature Corpus work: 83a0b9ba-bdcb-5ebe-89e7-70d5c5ab18ab
DOI: 10.1101/2025.03.13.25323915

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