Article

Assessment of heterogeneity and disease onset in the Parkinson’s Progression Markers Initiative (PPMI) cohort using the α-synuclein seed amplification assay: a cross-sectional study

2023-03-01

Abstract excerpt

<h4>Summary</h4> <h4>Background</h4> Recent research demonstrates that α-synuclein seed amplification assays (αSyn-SAA) accurately differentiate Parkinson’s disease (PD) patients from healthy controls (HC). We used the well-characterized, multicenter Parkinson’s Progression Markers Initiative (PPMI) cohort to further assess the diagnostic performance of αSyn-SAA and to examine whether the assay identifies heteroge...

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Literature Corpus work: d3ae8117-9955-55d6-9e34-51809e7c46c2
DOI: 10.1101/2023.02.27.23286156

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